Efficacy of ozonated water and chlorhexidine mouth rinse against plaque and gingivitis: A randomized clinical trial
Sujal Mitul Parkar, Kanchi Shah1, Nikhil Darjee1, Abhishek Sharma2
Aim: The aim of this study was to compare the efficacy of ozonated water and chlorhexidine mouth rinse against plaque and gingivitis. Materials and Methods: A randomized, double‑blind clinical trial was conducted. A total of 54 patients suffering from generalized chronic gingivitis were chosen for the study. The trial period of 15 days was divided into three time‑intervals, that is, baseline (0 day), 7th day and 15th day. The use of ozonated water, 0.2% chlorhexidine, and water irrigation was randomized. The clinical parameters such as plaque and gingival status were assessed using Turkesky‑Gilmore‑Glickman Modification of Quigley – Hein Plaque Index and Loe and Silness Gingival Index, respectively. The repeated one‑way analysis of variance followed by post hoc Bonferroni test was used for statistical analysis. The level of significance was considered at 5%. Results: The analysis was performed on 47 patients at the end of 15th day. There was a highly significant difference (P < 0.001) when the mean plaque and gingival scores were compared between three different interval of time. There was a significant difference (P = 0.002) when the mean plaque scores for chlorhexidine and water were compared. There was a significant difference when the mean gingival scores for ozonated water and chlorhexidine (P = 0.002) were compared. Conclusion: The results of this study demonstrate that ozonated water was as equally effective as chlorhexidine in reducing plaque and gingivitis with slight edge over chlorhexidine.
Key words: Chlorhexidine, mouthwash, ozone, randomized clinical trial.